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名稱:4,6-二羥基嘧啶
 

純度:99% 包裝:25kg/桶
結構式
                                        

CAS:   1193-24-4
分子式:  C4H4N2O2
分子量:  112.09

中文名稱:   4,6-二羥基嘧啶
                    6-羥基-4(1H)嘧啶酮
                    雙羥嘧啶

英文名稱:   6-hydroxy-4(1H)-Pyrimidinone
                    6-hydroxy-4(1h)-pyrimidinon
                    4,6-dihydroxypyrimidin 

性質描述:  白色或淺黃色針狀結晶。熔點338℃(230℃)。溶于熱水、氨水和其他堿類溶液,不溶于醇和醚。該品可能有幾種異構型式。 

質量標準:
含量               ≥98.0%
外觀              黃色或淡黃色粉末
干燥失重          ≤0.5%

甲醇                 ≤0.1%
丙二酸二甲酯 ≤0.1%
甲酰胺          ≤0.2%

用途:  用作有機合成中間體,在醫藥工業中用來生產磺胺類藥磺胺間甲氧嘧啶。它也是維生素B4、抗腫瘤藥及輔助藥類的中間體。

Product Identification
【Product Name】4,6-Dihydroxypyrimidine   4,6-二羥基嘧啶
【Synonyms】4,6-Pyrimidinediol
【CAS】1193-24-4
【Formula】C4H4N2O2
【Molecular Weight】112.09
【EINECS】214-772-3
【RTECS】UW7523000
【RTECS Class】Mutagen
【Beilstein/Gmelin】606433

Physical and Chemical Properties
【Appearance】Yellow orange powder.
【Solubility in water】2.5 g/L (20 C)
【Melting Point】> 300
【Partition Coefficient】.1

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Inhalation】Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
【Skin】Causes skin irritation.
【Eyes】Causes eye irritation. May cause chemical conjunctivitis.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Effects may be delayed.

Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Disposal Code】3
【Incompatibilities】Oxidizing agents.
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information
【HS Code】2933 59 95



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